Abstract
Summary The intraperitoneal injection of KCN, with or 10 min after the injection of Na 2 SeO 3 , reduced the acute toxicity of the selenite. Na 2 SeO 3 also reduced KCN toxicity. The addition of 200 μg KCN/ml to the drinking water partially prevented chronic selenosis in rats fed a diet containing added Na 2 SeO 3 (9 μg Se/g). Adding the KCN to the diet had no effect. The injection of KCN with Na 2 SeO 3 delayed the exhalation of Se by the rats. The possiblity that the effects noted were the result of SeCN − formation are discussed. The protective effect of linseed oil meal against selenosis can probably be explained by the release of CN − from its cyanogenic glycosides.
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