Partial breast irradiation with intraoperative radiotherapy in the ELIOT trial – Authors' reply

Abstract

We would like to thank our colleagues for their interest in the updated ELIOT trial.1 By showing a higher local relapse rate in the accelerated partial breast irradiation group, we do not intend to discourage the use of electron intraoperative radiotherapy (ELIOT)—let alone of accelerated partial breast irradiation in general—but rather to underscore the importance of appropriate patient selection. The ELIOT trial has identified a subgroup of patients with a notably low rate of local recurrence after either accelerated partial breast irradiation or whole-breast irradiation.