Pars Plana Filtration with Multiple Laser Perforation of the Uvea for Neovascular Glaucoma Following Proliferative Diabetic Retinopathy

Abstract

Purpose: To evaluate the effect of pars plana filtration with multiple laser perforation of the uvea in neovascular glaucoma patients following proliferative diabetic retinopathy. Methods: In 18 eyes of 13 patients, after a fornix-based conjunctival incision, two 9 × 3 mm, thin, rectangular scleral flaps were created 3–6 mm posterior to the limbus. The remaining layers of sclera under each flap were removed. The exposed uvea was irradiated at a mean of 60.6 spots with an argon laser just to the point of perforation. After the posterior chamber fluid escaped, the flaps were sutured. Results: The mean preoperative intraocular pressure (IOP) was 36.4 ± 9.0 mm Hg. After an average follow-up of 16.6 ± 5.9 months, the mean final postoperative IOP was 16.6 ± 4.4 mm Hg. The postoperative IOP was below 21 mm Hg in 3 (16.7%) of the 18 eyes without medication, in 14 (77.8%) on anti-glaucoma eye drops, and in 16 (88.9%) on anti-glaucoma eye drops and an oral carbonic anhydrase inhibitor. Snellen visual acuity improved by more than 2 lines in 7 of the 18 eyes, worsened by this amount in 3, and remained within baseline ± 2 lines in 8. Conclusion: This procedure is an effective treatment for neovascular glaucoma patients following proliferative diabetic retinopathy.