Abstract
The pars cohort study (PCS) is a 10-year cohort study aiming to investigate the burden and the major risk factors of non-communicable diseases, and to establish a setting to launch interventions for prevention of these diseases and controlling their risk factors. All inhabitants of Valashahr district in South of Iran, aged 40-75years, were invited to undergo interviews and physical examination, and to provide biological samples. A total of 9264 invitees accepted to participate in the study (95% participation rate) and were recruited from 2012 to 2014. Active follow-up was also carried out after 12months. About 46% of participants were male and 54% were female. About 14.0% of the participants were current smokers and 8.4% were ever opium users. The prevalence of overweight and obesity were 37.3 and 18.2%, respectively. The prevalence of hypertension was 26.9%. A total of 49 participants died during a median follow-up of one year. PCS with its large scale and wealth of socio-economic and medical data can be a unique platform for studying the etiology of non-communicable diseases and effective interventions in Iran.
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