Abstract
Parry-Romberg Syndrome, also known as Progressive Hemifacial Atrophy, is an uncommon degenerative condition, characterized by a slow and progressive atrophy affecting one side of the face. A cerebral disturbance of fat metabolism, atrophic malformation of Cervical Sympathetic Nervous System has been proposed as the primary cause. Other possible factors that are involved in the pathogenesis include trauma,viral infections, heredity, endocrine disturbances and auto-immunity. The objective of this work is, to accomplish a literature review concerning general characteristics, etiology, physiopathology, differential diagnosis and treatment of progressive hemifacial atrophy. A review of literature with variety of treatment options have been discussed in an attempt to treat the atrophic deformties from mild to severe cases. These have included free fat grafts, dermis fat grafts, fascia,muscle grafts, cartilage and bone augmentation ,Orthognathic surgery,microvascular reconstruction and stem cell regeneration of bone and soft tissues.
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