Abstract

Paroxysmal nocturnal haemoglobinuria is a disease of unknown aetiology which is sometimes present at birth. It is characterized clinically by anaemia and passage of urine in the morning containing haemolyzed blood. Diagnosis is confirmed by a positive Ham's test, a low level of alkaline phosphatase within neutrophils and positive titres of certain complement fixation fractions. An acute abdominal emergency is one of the many ways in which this condition may present (Dacie, 1967). This report concerns a patient who was admitted on two occasions with clinical features of an “acute abdomen”. The radiological findings on barium examinations of the gastro-intestinal tract are described and show this disease not only to be a cause of multiple lesions involving both the stomach and small intestine, but to have possibly contributed to her recovery by leading to appropriate treatment. A.T., a 31-year-old Jamaican woman, presented with severe abdominal pain and vomiting. She was found to have marked tenderness and ...

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