Abstract

The prevalence of Parkinson’s disease (PD) in the elderly population exceeds 1% according to recent reports, whereas myasthenia gravis (MG) is much rarer. The expected prevalence of the combination of MG and PD can be grossly estimated to 3 cases per 6 million. To our knowledge, since 1987, 12 cases of concurrent PD and MG have been reported . We report a new case of PD associated with MG with update literature review.

Highlights

  • The prevalence of Parkinson’s disease (PD) in the elderly population exceeds 1% according to recent reports, whereas myasthenia gravis (MG) is much rarer [1]

  • We report a new case of PD associated with MG with update literature review

  • Head drop in PD results from cervical dystonia or camptocormia, whereas in MG it is induced by neck muscle weakness [6]

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Summary

Introduction

The prevalence of Parkinson’s disease (PD) in the elderly population exceeds 1% according to recent reports, whereas myasthenia gravis (MG) is much rarer [1]. A 73-year old man with a 20-year history of akineto-hypertonic form of Parkinson’s disease, presented with fluctuating ptosis, diplopia, slurring of speech, dysphagia and general weakness of the neck, trunk and four limbs. These symptoms worsened during the course of the day but were better in the morning and after rest. Injection of Neostigmine dramatically improved his ptosis, slurred speech, dysphagia and muscle weakness.

Discussion
Weakness of the limbs and neck flexor muscles and ophtalmoplegia
Conclusion
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