Abstract

BackgroundWe sought to elicit preference weights from parents for health states corresponding to children with various levels of severity of atopic dermatitis. We also evaluated the hypothesis that parents with children who had been diagnosed with atopic dermatitis would assign different preferences to the health state scenarios compared with parents who did not have a child with atopic dermatitis.MethodsSubjects were parents of children aged 3 months to 18 years. The sample was derived from the General Panel, Mommies Sub-Panel, and Chronic Illness Sub-Panel of Harris Interactive. Participants rated health scenarios for atopic dermatitis, asthma, and eyeglasses on a visual analog scale, imagining a child was experiencing the described state.ResultsA total of 3539 parents completed the survey. Twenty-nine percent had a child with a history of atopic dermatitis. Mean preference scores for atopic dermatitis were as follows: mild, 91 (95% confidence interval [CI], 90.7 to 91.5); mild/moderate, 84 (95%CI, 83.5 to 84.4); moderate, 73 (95%CI, 72.5 to 73.6); moderate/severe, 61 (95%CI, 60.6 to 61.8); severe, 49 (95% CI, 48.7 to 50.1); asthma, 58 (95%CI, 57.4 to 58.8); and eyeglasses, 87(95%CI, 86.3 to 87.4).ConclusionsParents perceive that atopic dermatitis has a negative effect on quality of life that increases with disease severity. Estimates of parents' preferences can provide physicians with insight into the value that parents place on their children's treatment and can be used to evaluate new medical therapies for atopic dermatitis.

Highlights

  • We sought to elicit preference weights from parents for health states corresponding to children with various levels of severity of atopic dermatitis

  • Fivenson et al [9] found that 50% of the total burden of illness of atopic dermatitis is associated with lost productivity

  • We evaluated the hypothesis that parents with children who had been diagnosed with atopic dermatitis would assign different preferences to the health state scenarios compared with parents who did not have a child with atopic dermatitis

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Summary

Introduction

We sought to elicit preference weights from parents for health states corresponding to children with various levels of severity of atopic dermatitis. Atopic dermatitis can disrupt sleep in patients and their family members, and parents can miss work or avoid outside work altogether to care for a child with the disease [4,8]. Fivenson et al [9] found that 50% of the total burden of illness of atopic dermatitis is associated with lost productivity They found that days lost from work and nights of sleep lost were high among parents of young children with atopic dermatitis [9]. These stresses take additional tolls on familial relationships and are confounded in lowincome families, who often have minimal access to social support mechanisms [4]

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