Abstract

Background: Coronavirus disease 2019 (COVID-19) requires mass immunization to control the severity of symptoms and global spread. Data from developed countries have shown a high prevalence of parental COVID-19 vaccine hesitancy. However, parental vaccine hesitancy data in low- and middle-income countries are scarce. This study aimed to assess the prevalence of parental vaccine hesitancy and identify subgroups with higher odds of vaccine hesitancy in parents in Bangladesh. Methods: A cross-sectional study was conducted on the parents of children aged <18 years from October 10, 2021 to October 31, 2021. Parents participated in face-to-face interviews in randomly selected locations in Bangladesh using a vaccine hesitancy questionnaire. Factors associated with COVID-19 vaccine hesitancy were identified using binary logistic regression analysis. Results: Data from 2,633 eligible parents were analyzed. Overall, 42.8% reported COVID-19 vaccine hesitancy for their youngest child. The final model suggested the following factors were associated with hesitancy: children's age; parent's age, religion, occupation, monthly household income, permanent address, living location, status of tobacco use, adherence with regular government vaccination programs (other than COVID-19), perceptions ofCOVID-19 vaccine efficacy among Bangladeshi children, self-vaccination intentions, reported family members' illness or death from COVID-19, and perceived threat of COVID-19 were the independent predictors of parental COVID-19 vaccine hesitancy. Conversely, participants who were not tobacco users, parents who were very likely to believe that their children or family members could be infected with COVID-19 in the following year and who were very concerned about their children or a family member contracting COVID-19 in the next year had significantly lower odds of COVID-19 vaccine hesitancy. Conclusions: Our study suggested that vaccine hesitation varied based on sociodemographic characteristics, religion, behavior, and perceived COVID-19 threat. Therefore, interventions focused on addressing vaccine hesitancy among specific subgroups are warranted.

Highlights

  • Mass immunization against coronavirus disease 2019 (COVID-19) is one of the heaviest relied upon measures to control the spread of symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) and end the global pandemic.[1]

  • A total of 177 (6.3%) parents did not adhere to the regular government vaccination programs other than COVID-19, and 1,458 (55.4%) remained skeptical about the effectiveness of the COVID-19 vaccine for Bangladeshi children

  • 722 (27.4%) parents were either not vaccinated or did not receive the COVID-19 vaccine; 752 (28.6%) parents reported that they or their family members tested positive for COVID-19, and 151 (5.7%) had lost a family member to COVID-19

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Summary

Introduction

Mass immunization against coronavirus disease 2019 (COVID-19) is one of the heaviest relied upon measures to control the spread of symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) and end the global pandemic.[1]. Many countries have targeted vaccinating at least 80% of their total population, including individuals aged 18 years and below, to achieve herd immunity.[2,3]. Coronavirus disease 2019 (COVID-19) requires mass immunization to control the severity of symptoms and global spread. Data from developed countries have shown a high prevalence of parental COVID-19 vaccine hesitancy. Parental vaccine hesitancy data in low- and middle-income countries are scarce. The final model suggested the following factors were associated with hesitancy: children's age; parent's age, religion, occupation, monthly household income, permanent address, living location, status of tobacco use, adherence with regular government vaccination programs (other than COVID-19), perceptions of COVID-19 vaccine efficacy among Bangladeshi children, self-vaccination intentions, reported family members' illness or death from COVID-19, and perceived threat of COVID-19 were the independent predictors of

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