Abstract

Precision medicine relies upon artificial intelligence (AI)-driven technologies that raise ethical and practical concerns. In this study, we developed and validated a measure of parental openness and concerns with AI-driven technologies in their child’s healthcare. In this cross-sectional survey, we enrolled parents of children <18 years in 2 rounds for exploratory (n = 418) and confirmatory (n = 386) factor analysis. We developed a 12-item measure of parental openness to AI-driven technologies, and a 33-item measure identifying concerns that parents found important when considering these technologies. We also evaluated associations between openness and attitudes, beliefs, personality traits, and demographics. Parents (N = 804) reported mean openness to AI-driven technologies of M = 3.4/5, SD = 0.9. We identified seven concerns that parents considered important when evaluating these technologies: quality/accuracy, privacy, shared decision making, convenience, cost, human element of care, and social justice. In multivariable linear regression, parental openness was positively associated with quality (beta = 0.23), convenience (beta = 0.16), and cost (beta = 0.11), as well as faith in technology (beta = 0.23) and trust in health information systems (beta = 0.12). Parental openness was negatively associated with the perceived importance of shared decision making (beta = −0.16) and being female (beta = −0.12). Developers might support parental openness by addressing these concerns during the development and implementation of novel AI-driven technologies.

Highlights

  • Precision medicine offers the hope of transforming healthcare by developing more accurate and effective strategies to diagnose, prevent, and treat diseases by considering an individual’s genetic, environmental, and lifestyle characteristics [1,2]

  • We developed a framework of nine factors that might influence openness to artificial intelligence (AI)-driven healthcare interventions in pediatrics: privacy, transparency, human element of care, social justice, societal cost, personal cost, quality/accuracy, access to care, and access to knowledge

  • We developed the first measure of openness to AI-driven healthcare interventions in pediatrics

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Summary

Introduction

Precision medicine offers the hope of transforming healthcare by developing more accurate and effective strategies to diagnose, prevent, and treat diseases by considering an individual’s genetic, environmental, and lifestyle characteristics [1,2]. To fulfill these hopes, precision medicine interventions require access to vast amounts of personal-level data and patient information, as well as artificial intelligence (AI) algorithms capable of analyzing these large datasets [3]. These evolving AI-driven technologies raise ethical and practical concerns [3], especially in pediatrics.

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