Abstract
The exciting developments in the understanding and management of osteodystrophy, due to primary hyperparathyroidism, are being recapitulated. We are now attacking the osteodystrophies produced by secondary hyperparathyroidism, which is due to chronic renal failure. Although the osseous changes of chronic renal failure have been observed for decades, the eventual terminal fatal course of chronic renal failure patients has precluded any surgical approach. Significant advances in recent years in nephrology have, in selected patients, reversed the inevitable downhill course of chronic renal failure by regular dialysis. These therapeutic accomplishments have not only allowed long-term survival in these particular patients but have also allowed the osseous changes to progress into a state of clinical significance and invalidism in patients whose general health has otherwise been good. Our purpose in this study will be to deal in particular with chronic renal failure patients whose osseous changes are induced by a state of secondary
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