Abstract
Physiological overgrowth of the parathyroid glands in mammals has been very rarely observed. Erdheim,1 Bauer2 and Strada3 have recently described its occurrence in man in association with some cases of osteomalacia. Three instances of undoubted general parathyroid enlargement in bitches in association with lactation have come under my observation.In the reports of partial removal and of transplantation of mammalian parathyroids, particularly in dogs, one of the most characteristic features has been the absence of any noteworthy compensatory enlargement of the remaining portion within the time limits in which other tissues, like the thyroid, heart muscle, kidney, etc., react to artificially induced insufficiencies.In the course of some experiments with the thyroid gland in fowls in 1910, I observed several instances of marked enlargement of the parathyroids independent of the changes occurring in the thyroid glands. These parathyroid changes were found in fowls which had been fed with maize and wheat for p...
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