Abstract
Parathyroid hormone (PTH) and PTH-related protein (PTHrP) stimulate the PTH-1 receptor and inhibit keratinocyte proliferation in vitro. PTHrP is expressed in the nonbasal layers of normal epidermis but not in psoriatic epidermis, and PTHrP expression is restored after treatment with topical calcipotriene. To investigate whether PTH or related proteins can improve psoriasis, …
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