Parathyroid hormone-related protein and primary teeth eruption in stunting children

Abstract

Stunting is a linear growth failure as an indicator of malnutrition status which is identified by comparing the height of children with normal height according to the same age and sex. Children are categorized as stunting if the child`s height is shorter than the average height of the same age and sex and has a standard deviation of below minus 2 according to the standard who. The cause of stunting is multifactorial, including disruption of hormone function, one of which is a parathyroid hormone. Parathyroid Hormone-related Protein (PTHrP) plays a role in the tooth-eruption process. This literature review aims to study the role of PTHrP on the eruption rate of primary teeth in stunting children. Malfunction of the parathyroid glands in stunted children can cause a deficiency of PTHrP levels. PTHrP and vitamin D play a role in the maintenance and affect calcium levels. Deficiency levels of PTHrP and vitamin d can lead to decreased absorption of calcium in the blood. Calcium deficiency in children can cause osteoclasts and osteoblasts to decrease, which can affect bone growth and tooth eruption patterns. In stunting children, the level of PTHrP will decrease so that tooth eruption will be inhibited.