Abstract
SummaryThe stimulation of DNA synthesis and mitotic activity in liver cells after partial hepatectomy is reduced to about 50% of their normal value and delayed 12 to 14 hr in parathyroidectomized rats. It has also been observed that partial hepatectomy, itself, induces an early, transient, hypocalcemia which precedes the initiation of DNA synthesis and cell proliferation. These observations suggest that the parathyroid hormone might be a humoral agent involved in the initiation of hepatic regeneration.
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