Abstract
Parathyroid cysts were produced in rats by excessive doses of dihydrotachysterol.(DHT) and calcium acetate. Although overdoses of each DHT, calcium or their combination are believed to suppress the activity of the parathyroid cell, the present electron microscopic observation showed signs of enhanced protein synthesis and secretion of the cells in all stages of cyst formation. It seems reasonable to assume that this cyst formation depends upon two main processes: retention of secretory material in the intercellular spaces and liquefaction necrosis of the paratkyroid cells which emerges in rather later stages of cyst formation.
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