Abstract
BACKGROUND: Parathyroid carcinoma accounts for less than 1% of cases of primary hyperparathyroidism. Clinical presentation is usually related to severe hypercalcemia associated to elevated serum PTH (three times above the upper limit). These values are so much higher than in primary hyperparathyroidism due to a benign adenoma. Moreover, 30-75% of patients usually have a palpable neck mass at presentation.
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