Parasite-Derived Components: An Updated Review of the Toxicological and Pharmacological Effects on the Host

Abstract

The toxicological and pharmacological effects of parasite-derived components on the host have received extensive attention. A deep understanding of the toxicological and pharmacological effects of parasite-derived molecules on the host from the perspective of co-adaptation formed during the long-term parasite-host evolution process will not only deepen the understanding of the pathogenic mechanisms of parasites from the perspective of pathogenesis but also benefit from the perspective of treatment. From the perspective of disease, research and development based on the transformation and application of insect-derived components have become and will continue to be one of the most popular research tasks in the field of parasitology research. This article reviews the toxicological and pharmacological effects of several essential zoonotic parasites and their parasites in recent years in inducing and regulating host immune metabolism-related diseases and makes suggestions for the future direction of parasitology research.