Paraplegia secondary to metastatic prostatic carcinoma treated with stilbestrol; report of a case.

Abstract

Case Reports1 December 1949PARAPLEGIA SECONDARY TO METASTATIC PROSTATIC CARCINOMA TREATED WITH STILBESTROL: REPORT OF A CASEISIDORE S. EDELMAN, M.D.ISIDORE S. EDELMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-6-1098 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONTransverse interruption of spinal cord function occurs relatively infrequently as a result of metastases from carcinoma of the prostate. Bumpus1 reported that 11 of 1,000 untreated patients with carcinoma of the prostate had symptoms simulating tumor of the cord with some paralysis prior to death. In those patients with cord compression by metastatic tumor and loss of motor power, loss of sphincteric control and associated ascending urinary tract infection, palliation becomes a problem of prime importance.The beneficial palliative effects of orchiectomy and/or estrogenic therapy in the treatment of advanced prostatic carcinoma are well known.2, 3, 4, 5, 6...Bibliography1. BUMPUS HC: Carcinoma of the prostate, Surg., Gynec. and Obst., 1926, xliii, 150-155. Google Scholar2. HERGERSAUER CCHR: A consideration of the effect of androgen control treatment of carcinoma of the prostate, N. Y. State Jr. Med., 1947, xlvii, 494. Google Scholar3. DEMING CL: The hormonal treatment of prostatic malignancy, Bull. N. Y. Acad. Med., 1946, xxii, 88. Google Scholar4. NESBITCUMMINGS RMRH: Prostatic carcinoma treated by orchiectomy, Jr. Am. Med. Assoc., 1942, cxx, 1109. CrossrefGoogle Scholar5. HUGGINS C: Prostatic cancer treated by orchiectomy: the five year results, Jr. Am. Med. Assoc., 1946, cxxxi, 576. CrossrefGoogle Scholar6. NESBIT RM: Cancer of the prostate: general considerations, N. Y. State Jr. Med., 1947, xlvii, 376. Google Scholar7. YOUNG HA: The cure of cancer of the prostate by radical perineal prostatectomy, Jr. Urol., 1946, liii, 188-256. Google Scholar8. GUTMAN AB: Serum acid phosphatase in patients with carcinoma of the prostate gland, Jr. Am. Med. Assoc., 1942, cxx, 1113. Google Scholar9. WRAY S: Blood acid phosphatase in prostatic cancer, The Lancet, 1945, i, 783. CrossrefGoogle Scholar10. CLARKEVIETS BGHR: Effect of diethylstilbestrol on neurologic symptoms of carcinoma of the prostate, Jr. Am. Med. Assoc., 1943, cxxi, 499. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication February 7, 1948.From the division of Neoplastic Diseases, Montefiore Hospital, New York, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe Role of Surgery in the Management of Metastatic Spinal TumorsCurrent Concepts of Systemic Therapy of Spinal TumorsControversies in the management of metastatic spinal cord compressionManifestations of Advanced Prostate Cancer: Prognosis and TreatmentSpinal cord compression in myelomatosis: Response to chemotherapy aloneEffective systemic therapy for spinal epidural metastases from breast carcinomaParaplegia and paraparesis due to prostatic cancerAnalysis of medical treatment of malignant extradural spinal cord tumorsAn evaluation of surgical treatment for spinal cord compression due to metastatic carcinomaSpinal Cord Compression Secondary to Metastatic Carcinoma of the Prostate Treated by Decompressive LaminectomyTreatment of metastatic extradural spinal cord tumors.A series of 30 casesParaplegia Due to Vertebral Metastasis of Prostatic Carcinoma: Case Report 1 December 1949Volume 31, Issue 6Page: 1098-1102KeywordsEstrogensMetastatic tumorsOrchiectomyPalliative careParalysisParaplegiaProstate diseasesSpinal cord ePublished: 1 December 2008 Issue Published: 1 December 1949 PDF downloadLoading ...