Abstract
Both benign and malignant tumors may arise from any of the structures contained within the parapharyngeal space. Parapharyngeal space is difficult to reach and formidable area to approach by any surgeon. Due to its deep placement and approximation to vital structures, not only is tumour involving this space a difficult task to manage for the surgeon, but even its diagnosis may elude the doctor. Even the battery of clinical, biochemical or radiological tests diagnosis remains a difficult objective. We aim to provide an adjunct mode of aiding the diagnosis in the form of tumour markers. Though tumour markers alone are not sufficient, with the help of other tests, the diagnosis can be reached in a fairly accurate measure.
Highlights
The parapharyngeal space (PPS) is a potential space in the form of an inverted pyramid, with the base at the skull base and the tip at the hyoid bone
Salivary gland neoplasms are located in prestyloid space and account for about 40% - 50% of parapharyngeal space tumors
Two cases each of Neuroendocrine tumor and Schwannoma were operated via Transcervical approach
Summary
The parapharyngeal space (PPS) is a potential space in the form of an inverted pyramid, with the base at the skull base and the tip at the hyoid bone. The tensor veli palatini muscle attaching to styloid process divides the space into prestyloid and poststyloid spaces [1]. Both benign and malignant tumors may arise from any of the structures contained within the parapharyngeal space. 70% - 80% are benign, and 20% - 30% are malignant [2]. Most parapharyngeal space tumors are of salivary or neurogenic origin. Salivary gland neoplasms are located in prestyloid space and account for about 40% - 50% of parapharyngeal space tumors (mostly pleomorphic adenomas of deep lobe). Neurogenic lesions are the most common tumors of the poststyloid parapharyngeal space and account for 25% - 30% of parapharyngeal space lesions (mostly neurilemomas i.e. shwannomas).
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