Abstract
In 1999, a 65-year-old man presented to our hospital with a generalised, painless weakness of the limb muscles, which was most pronounced in the proximal leg muscles. Within the next 6months the patient's strength progressively deteriorated and he could only walk up to 10m. The clinical examination revealed a weakness and subtle atrophy of the proximal muscles of both legs. Electrophysiological studies revealed signs of acute and chronic denervation in the affected muscles. Of all the routine laboratory variables examined, serum concentrations of creatine kinase (CK) were increased to 2010 U/mL at admission (figure).
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