Abstract
Paraneoplastic cerebellar degeneration and limbic/brainstem encephalopathy associated with small cell lung cancer with serum positivity for anti-Hu and multiple anti-ganglioside (GM2, GQ1b, GaLNAc-GD1a, GT1a) antibodies: A case report
Highlights
Anti-Hu antibodies are known to appear in paraneoplastic neurologic syndrome associated with small cell lung cancer
This is the first reported case of cerebellar degeneration and limbic/brainstem encephalopathy accompanied by small cell lung cancer; in this case, the patient was positive for anti-Hu and multiple anti-ganglioside antibodies
The implications of anti-ganglioside antibody production in cancer should be elucidated in the future, and a screening of ganglioside antibodies should be recommended as a potential future study
Summary
This is the first reported case of cerebellar degeneration and limbic/brainstem encephalopathy accompanied by small cell lung cancer; in this case, the patient was positive for anti-Hu and multiple anti-ganglioside antibodies.
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