Abstract

Scleromyxedema is a rare, chronic and progressive disorder of unknown origin characterized by a generalized papular eruption and sclerodermoid induration, with histopathologic features of mucin deposition and fibroblast proliferation.1 The disease is usually associated with a monoclonal gammopathy.1, 2 However, only a few cases associated with neoplasms have been reported.1, 3 We report a case of paraneoplastic scleromyxedema with advanced gastric cancer.

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