Abstract

A parallel Frequency Domain Optical Coherence Tomography (FD-OCT) system and - to the best of our knowledge- first in vivo tomograms obtained with such system are presented. A full tomogram of 256(x) x 512(z) pixels covering a sample region of 8 mm x 3,8 mm is recorded in only 1 ms. Since the transverse as well as the depth information is obtained in parallel, the structure is free of any motion artifacts. In order to study cross talk issues for parallel illumination the transversal resolution for a thermal light source is compared to that with an SLD.

Highlights

  • Recent works on Fourier Domain Optical Coherence Tomography (FD OCT) - first introduced to the field of biomedical imaging by Fercher et al in 1995 [1] - demonstrated the impressive potential of this technique to perform fast in-vivo imaging of biological tissue with high sensitivity as well as high resolution

  • In conclusion a parallel FD OCT system is presented that is capable of imaging biological structures in vivo

  • To the best of our knowledge the first in vivo tomograms obtained with a full parallel FD OCT system are presented

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Summary

Introduction

Recent works on Fourier Domain Optical Coherence Tomography (FD OCT) - first introduced to the field of biomedical imaging by Fercher et al in 1995 [1] - demonstrated the impressive potential of this technique to perform fast in-vivo imaging of biological tissue with high sensitivity as well as high resolution. Still one needs to perform lateral scanning of the sample that limits the imaging speed. Parallel time domain OCT was a first step to avoid the lateral scanning by recording the full transversal object structure synchronously with a smart pixel detection array [8]; still, the necessary depth scanning limited the achievable tomogram rate. In 1999 Zuluaga and Richards-Kortum [10] reported a fully parallel FD OCT system that needs neither lateral nor longitudinal scanning. They imaged a fixed technical sample for demonstrating the principle. The content of the current work is to present a fully parallel FD OCT system that allows invivo real time imaging of human eye structures. The motivation is to use the measured data as input to ray tracing routines that allow a true geometrical reconstruction of eye interfaces and their topology [11]

Experimental setup
Laser safety issues
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