Abstract
The need for independent dual detection in the analysis of complex mixtures by gas chromatography-chemical-ionization mass spectrometry is illustrated. Monitoring of the gas chromatographic effluent by means of universal detection and unaltered uniform response by flame ionization detection is a desirable supplement to the customary, highly selective, monitoring of the total ion current, especially in consecutive analyses of the same sample, where the chemical-ionization reagent gas is varied. Since the gas chromatograms obtained by flame ionization detection are unaffected by changes in chemical-ionization conditions, they provide a safer common basis for interrelating spectral data from successive runs than do the total ion current records. For the special case of reconstructed gas chromatograms generated by computers from digitized total ion current values, direct correlations are conveniently achieved by calibrating both the flame ionization detection and total ion current records in spectrum index numbers through the use of an event marker, triggered by the data system.
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