Abstract

A case of a carrier of two albumins in the urine is described. The percentual values of serum and urinary proteins obtained by paper electrophoresis are presented. The results of this analysis demonstrated a genetic defect accompanied by an evident nephrotic syndrome that, in the final stages of the disease, allowed complete passage of the albumin into the urine. Using an improved resolution method, buffered and un-modified urines were studied. The electropherogram of the ascitic fluid was similar to that of serum. Other complementary tests were also carried out. Comparing the relative percentages of normal and abnormal albumins (discounting in the latter the value of α 1-globulin) it can be seen that each had a value of approximately half of the complete albumin fraction.

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