Abstract

Paradoxical vocal fold motion disorder (PVFMD) is a disease characterized by intermittent adduction of the vocal folds during inspiration and/or expiration, causing dyspnea and sensation of throat tightness. Usually there are intermittent symptoms of shortness of breath and inspiratory stridor that may lead patient to emergency units. The disease is frequently misdiagnosed and many patients are treated wrongly. Some neurologic alterations are accused but the etiology is still unclear. The diagnostic work-up should include a detailed history and physical examination, pulmonary function testing, measures of oxygenation and flexible laryngoscopy. Asthma, laryngopharyngeal reflux, some air irritants and some psychologic conditions should be ruled out in differential diagnosis.

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