Abstract

The role of dental foci of chronic infection is well known. The majority of works are devoted to tonsillar and dental (periapical) foci. Although the focus of chronic inflammation in the periodontium is considered to be well-drained, modern periodontologists believe that it has exceptional pathogenicity. Currently, the connection between the pathogenic action of periodontal disease and periodontal pockets has been revealed, and, as confirmed by us, regardless of the nosological affiliation of periodontal disease. Thus, comparing the indices of immunobiological state of the body (the activity of lysozyme of mixed and parotid saliva, blood serum, the concentration in blood of serum immunoglobulins G, A and M, the level of circulating immune complexes (CIC) and the frequency of microbial sensitization) in patients with chronic gingivitis, periodontitis and periodontitis we found significant changes in these indicators only in patients burdened with periodontal pockets.

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