Abstract
Much less is known about how bacteria segregate DNA prior to replication than is known about such processes in eukaryotic cells. Most bacterial chromosomes contain homologs of plasmid partitioning (par) loci. These loci encode ATPases called ParA that are thought to contribute to the mechanical force required for chromosome and plasmid segregation, but the mechanisms by which these ATPases function in segregation are unknown. In Vibrio cholerae, the chromosome II (chrII) par locus is essential for chrII segregation.
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