Para testicular rhabdomyosarcoma in adults: three case reports and review of literature.

Lamiae Boudahna,Khadija Benhayoune,Yassir Tahiri,Aicha Mazouz,Afaf Amarti,Moulay Hassan Farih,Lamiae Amaadour,Zineb Benbrahim,Nawfel Mellas,Samia Arifi

doi:10.11604/pamj.2014.19.279.4784

Abstract

Paratesticular embryonal rhabdomyosarcoma (RMS) is a rare tumor arising from the mesenchymal tissues of the spermatic cord, epididymis, testis and testicular tunics. We report three cases of adult paratesticular RMS, two embryonic and one pleomorphic rhabdomyosarcoma. All the patients underwent diagnostic orchidectomy. The work up investigations revealed lung metastases. Chemotherapy with Ifosfamide and Doxorubicin was used in two cases, whereas Vincristin- Actinomycin D and Cyclophosphamide was received in one case. An objective partial response was reported in 2 cases, with complete response in one case. Paratesticular RMS is a rare and aggressive tumor. Because of the absence of protocols designed specifically for adult patients, it is necessary to follow therapeutic guidelines in pediatric protocols.

Highlights

Rhabdomyosarcoma (RMS) is a malignant tumor of mesenchymal origin thought to arise from cells committed to a skeletal muscle lineage
A 18-year-old patient who presented to the department of surgical urology with a painless scrotal mass, he underwent a left inguinal orchidectomy
A 19-year-old patient, presented to our oncology department, with paratesticular embryonic rhabdomyosarcoma diagnosed because a painless scrotal mass

Summary

Introduction

Rhabdomyosarcoma (RMS) is a malignant tumor of mesenchymal origin thought to arise from cells committed to a skeletal muscle lineage. The first documented case of spermatic cord sarcoma was described by Lesauvage in 1845 Since this date, few cases were reported in the literature especially in adult. A 18-year-old patient who presented to the department of surgical urology with a painless scrotal mass, he underwent a left inguinal orchidectomy. A 19-year-old patient, presented to our oncology department, with paratesticular embryonic rhabdomyosarcoma diagnosed because a painless scrotal mass. A 25-year-old patient presented to the department of surgical urology with a painless scrotal mass.

Discussion

Findings

Conclusion