Abstract
Pregnancy can influence the course of a number of dermatologic disorders. Interestingly, these disorders can also influence pregnancy outcomes negatively, due to a variety of underlying pathogenic mechanisms. These outcomes may range from low fetal birth weight, preterm birth, and miscarriages to perineal lacerations complicating deliveries. Our review highlights the impact that papulosquamous disorders may have on pregnancy and their course throughout pregnancy. We chose papulosquamous disorders due to their relatively high prevalence worldwide compared to other dermatologic disorders. This review also sheds light on any gaps in the literature relevant to this topic that should be addressed.
Highlights
BackgroundPregnancy is a time of immunologic, metabolic and hormonal changes, which can influence the course of a number of dermatologic conditions, many of which have an underlying immunologic nature
Knowledge regarding how different dermatologic disorders affect pregnancy is essential as it calls for a closer observation of the fetus and pregnancy, as a whole
It allows for the prediction of and preparation for any issues that may arise throughout pregnancy and at the time of delivery
Summary
Pregnancy is a time of immunologic, metabolic and hormonal changes, which can influence the course of a number of dermatologic conditions, many of which have an underlying immunologic nature. Skin manifestations during pregnancy can include physiologic changes such as hyperpigmentation, vascular skin lesions, and striae distansea [1,2]. Other cutaneous manifestations range from pregnancy-specific dermatoses such as polymorphic eruption of pregnancy, atopic eczema of pregnancy, and pemphigoid gestationis [3] to primary dermatoses unrelated to pregnancy including psoriasis and pityriasis rosea. Our review focuses on these primary dermatoses, papulosquamous diseases. Pregnancy can influence the prognosis of these conditions, with some worsening throughout pregnancy or the post-partum period, others improving or stabilizing [4]. Certain dermatoses were found to possibly impact pregnancy outcomes resulting in stillbirths, low birth weight, or prematurity amongst other complications, emphasizing the need for closer follow-ups and prompt management
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