Papillon–Lefèvre syndrome mimicking psoriasis – A rare case report

Abstract

Papillon–Lefèvre syndrome is a rare disease characterized by skin lesions caused by palmar-plantar hyperkeratosis and severe periodontal destruction involving both the primary and permanent dentitions. It is transmitted as an autosomal recessive condition and consanguinity of parents is evident in about one third of the cases. This paper reports a unique case of a patient with Papillon–Lefèvre syndrome (PLS) that was earlier mistaken for psoriasis. The examination revealed severe hyperkeratosis on the hands and feet with associated severe periodontal conditions. The patient was diagnosed with Papillon–Lefèvre syndrome and suitable treatment was initiated.