Abstract
Abstract Introduction: Papillary thyroid carcinoma is the most common form of thyroid malignancy. Numerous clinicopathologic studies have documented its generally indolent clinical course and excellent overall prognosis. However older patients have more aggressive disease with a worse prognosis. Material and Methods: A retrospective study was done, including all the patients who had presented to our department East Surgical ward of Mayo hospital, in Lahore during 8 years period from October 2006 to November 2013 with papillary thyroid carcinoma. Results: There were 30 male and 100 female patients, resulting in a male to female ratio of 1:3.33. The range was from 13 to 83 years, and the mean was 40 years. All the patients presented initially with clinically evident disease in the neck. This was located within the thyroid gland in 72 (67.2%), in the thyroid gland plus cervical nodes in 54 (41.5%), and in the cervical nodes only in 1 (0.76%). Conclusion: Total thyroidectomy followed by RAI therapy is the treatment of choice for primary and recurrent papillary thyroid carcinoma.
Highlights
Papillary thyroid carcinoma is the most common form of thyroid malignancy
Total thyroidectomy followed by RAI therapy is the treatment of choice for primary and recurrent papillary thyroid carcinoma
Clinically evident cervical lymphadenopathy at the time of presentation, with or without an accompanying thyroid mass, was noted in 54 patients (41.53%). 3 (2.30%) patients presented with thyroglossal cyst which was found to have papillary thyroid carcinoma
Summary
Papillary thyroid carcinoma is the most common form of thyroid malignancy. Papillary thyroid carcinoma (PTC) is the most common form of thyroid malignancy. Older patients have more aggressive disease with a worse prognosis. The treatment of papillary thyroid cancer is dependent on the biologic behavior of the tumor. The role of completion thyroidectomy, central neck dissection, and postoperative radioiodine (RAI) ablation to help prevent recurrent disease is all dependent on the malignant potential of the primary tumor. Prognostic factors as sex and age, tumor size, histologic type, tumor infiltration, vascular or lymphatic invasion, have been shown to affect survival in these patients [7]. Even in patients with metastatic disease, the overall survival in papillary thyroid cancer is higher
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