Abstract

Collision tumours refer to the presence of histologically different neoplasms of distinct origin in a single site. Papillary carcinoma of thyroid is one of the most common malignancy in the thyroid gland which is associated with good prognosis. Papillary carcinoma thyroid can metastasise to lymphnode however presence of squamous cell carcinoma and papillary carcinoma in cervical lymphnode (Collision tumour) is a rare presentation which is associated with bad prognosis and warrants appropriate treatment with a multidisciplinary approach. Here we present a 65 year old male who was diagnosed to have Collision metastasis (Squamous cell carcinoma and papillary carcinoma) in right cervical lymphnode. This case is presented due to its rarity, occurrence in a male patient and to emphasise the need for multidisciplinary approach including radiotherapist for treatment purposes. Presence of Squamous cell carcinoma and Papillary carcinoma (Collision Metastasis) in lymphnode could be due to Dedifferentiation of Papillary thyroid carcinoma at Metastatic site or Metastasis from Extrathyroidal Primary Squamous cell carcinoma. Immunohistochemistry would help in ascertaining the thyroid origin of the squamous cell component. Any clinically aggressive thyroid tumour must alert both the clinician and the pathologist as it warrants careful search for transformation to aggressive histological type of malignancy.

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