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Abstract
Recently, the incidence of papillary thyroid cancer increases rapidly than any other type of cancer worldwide, without the age and gender discrimination. Environmental or therapeutic exposure of radiation is main culprit of papillary thyroid cancer, but there is limited research available to support that to the usage of infertility drug associated with papillary thyroid cancer. We presented the rare and interesting case of papillary thyroid cancer while patient was on clomiphene citrate for the management of infertility. We found few studies which showed pathophysiology connection between in CC and papillary cell carcinoma.
Highlights
We found few studies which showed pathophysiology connection between in clomiphene citrate (CC) and papillary cell carcinoma
The thyroid gland is one of the essential endocrine glands in the human body located in front of the neck
Patient was on regular endocrine follow up for last 2 years, taking propylthiouracil and cabergoline and her hyperthyroidism was well controlled
Summary
The thyroid gland is one of the essential endocrine glands in the human body located in front of the neck. It uses iodine to produce hormone which regulates body temperature, heart rate, blood pressure and metabolic rate [1]. Thyroid cancer is most rapidly increasing cancer in men and women since 1975. The incidence of thyroid cancer has increased nearly three times, mostly the increase in papillary thyroid cancer (PTC). Risk factor for thyroid cancer can be hereditary, familial or environmental like exposure to the radiation, low iodine diet. There is minimal data suggesting correlation between use of hormonal therapy and papillary thyroid cancer. Papillary thyroid cancer has higher incidence but with better prognosis [3]
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