PAPILLARY ENDOTHELIAL HYPERPLASIA—A CASE REPORT OF THIS RARE VASCULAR LESION

Abstract

We will report a case of intravascular papillary endothelial hyperplasia, an unusual blood vessel disease occurring in the oral cavity. A female patient, 54 years of age, showed a bluish asymptomatic nodule in the lower lip, measuring 5 mm in diameter. The clinical diagnostic hypotheses were hemangioma or mucocele. An excisional biopsy was performed. The histopathologic examination demonstrated papillary tufts with a central hyaline core lined by a single layer of endothelial cells, which were positive for CD31 staining. The final diagnosis was papillary endothelial hyperplasia. This is a benign reactive vascular lesion with uncertain etiology. Scientific studies report this lesion as an organized thrombus. The treatment performed was surgical with a good prognosis. The 1-year follow-up period showed no signs of clinical recurrence.