Abstract

Papanicoleau Smear Usage and Prevalence of Premalignant Cervical Lesion among Women Living with HIV Attending a Federal Teaching Hospital in South-West Nigeria: A Comparative Study

Highlights

  • Human immunodeficiency virus (HIV) infection is associated with an increased risk of diverse cancers and has emerged as a single major factor in the recent accelerated burden of cancer in Sub-Saharan Africa [1]

  • The prevalence of premalignant cervical lesions among the study and control groups was 26.2% and 16.9% respectively. This showed that premalignant cervical lesion was more prevalent among HIV-positive women though not statistically significant (P=0.201)

  • There is need for the Physicians to use every opportunity to counsel their clients on the need for routine cervical cancer screening especially in adult HIV clinics

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Summary

Introduction

HIV infection is associated with an increased risk of diverse cancers and has emerged as a single major factor in the recent accelerated burden of cancer in Sub-Saharan Africa [1]. It is the best example of the close relationship between infection, immune dysfunction and evolution of malignancies. The findings are somewhat similar to the 2008 GLOBOCAN estimates for the whole co untry of 32.9 per 100 000 for the period 1998 to 2002 This suggests that the incidence of cervical cancer has remained largely stable over time. A very small percentage of women are currently on National Health Insurance Scheme [3]

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