Abstract
Oral antivirals have been an important addition to efforts to minimise adverse COVID-19 outcomes in individuals at high risk. Although no head-to-head comparisons of the widely available treatments molnupiravir and nirmatrelvir–ritonavir have been published, early trial findings (done largely in unvaccinated populations during pre-omicron SARS-CoV-2 waves) suggested less benefit from molnupiravir.
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