Abstract
Pannexins (Panx) constitute a new family of gap junction type proteins. Functional expression in paired Xenopus oocytes indicated that pannexins are capable of forming communicating junctions and proved to be active in forming of unapposed hemichannels. In the vertebrate brain pannexins have been found in neurons. However, the exact localization of pannexin proteins at the submicroscopical level in brain tissues is still enigmatic.
Highlights
Pannexins (Panx) constitute a new family of gap junction type proteins
Functional expression in paired Xenopus oocytes indicated that pannexins are capable of forming communicating junctions and proved to be active in forming of unapposed hemichannels
In the vertebrate brain pannexins have been found in neurons
Summary
Pannexins (Panx) constitute a new family of gap junction type proteins. Functional expression in paired Xenopus oocytes indicated that pannexins are capable of forming communicating junctions and proved to be active in forming of unapposed hemichannels. Pannexin1 is a novel protein component of postsynaptic sites Georg Zoidl*, Elisabeth Petrasch-Parwez, Arundhati Ray, Carola Meier, Stephanie Bunse, Hans-Werner Habbes, Gerhard Dahl and Rolf Dermietzel
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