PANKREATİTLİ ÇOCUKLARDA HEMATOLOJİK PARAMETRELERİN KLİNİK ÖNEMİ

Abstract

OBJECTIVE: In this study, we aimed to retrospectively evaluate the significance of new hematological parameters in the diagnosis of the inflammatory process of acute pancreatitis in children diagnosed with acute pancreatitis (AP) and acute recurrent pancreatitis (ARP). This is the first study in the literature assessing new hematological parameters (Red cell distribution width (RDW), red cell distribution width to calcium ratio (RDWCaR), neutrophile to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), platelet to lymphocyte ratio (PLR), Red cell distribution width to platelet ratio (RDWPR) and mean platelet volume (MPV)) in children with pancreatitis retrospectively. MATERIAL AND METHODS: The medical records of 55 patients, who were admitted to the hospital between January 2014 and December 2019 were diagnosed with AP and ARP, were examined retrospectively. RDW, RDWCaR, MPV, NLR, LMR, RDWPR and PLR values at 0 and 48 hours were evaluated retrospectively. Group 1 consists of patients with acute pancreatitis, Group 2 consists of patients with acute recurrent pancreatitis. A p value of <0.05 was considered statistically significant. RESULTS: RDW48h values of Group 1 and Group 2 were found to be significantly lower than RDW0h values (p<0.001 and p=0.006, respectively). RDWCaR48h values in both groups were also found to be significantly lower than RDWCaR0h (p= 0.003 and p= 0.012, respectively). NLR48h value was detected to be lower than NLR0h in Group 1 (p= 0.004). Moreover, the RDWPR48h value was found to be lower compared to RDWPR0h in Group 2 (p=0.041). CONCLUSIONS: In this study, we determined that RDW, RDWCaR, NLR and RDWPR values within the first 48 hours were important in the diagnosis and follow-up of children with AP and ARP.