Abstract

I wish to thank Professor Kaiser and Dr. Müller for having invited us to form this panel which is to discuss hyperuricaemia as a risk factor. I wrote to my colleagues about the four main topics which we are going to discuss today. We have to consider the extent to which hyperuricaemia may be a health risk factor, or an indicator of disease; whether it ever merits treatment in the absence of known complications, and if so, when and how it should be treated. We also have to identify the risks, or the alleged risks, and the importance of known or suspected pathophysiological factors, which may modulate the serum urate and urine uric acid concentrations in particular individuals. Under this heading, we have to think of such things as genetic, ethnic and dietary factors, sex and obesity.KeywordsUric AcidSerum Uric AcidSerum UratePurine Nucleoside PhosphorylaseUric Acid StoneThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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