Abstract
A new method of pancreaticore nal composite transplantation in a porcine model is presented aiming at reducing the risk of vascular throm bosis, which is still a frequent compli cation in pancreatic transplantation. In 14 technically successful duodeno pancreaticorenal allotransplantations (DPRTx) with joint venous drainage of pancreas and kidney and urinary drainage of the exocrine pancreas, euglycemia could be maintained in the substitutive transplant group (sDPRTx) and significant exocrine function (p = 0.222) in the auxiliary (aDPRTx) and substitutive trans plant group for up to four weeks. Pancreaticorenal composite trans plantation thus proved to be a prom ising new method combining hemo dynamic improvement in the pancre atic graft and gaining a kidney at the same time.
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