Abstract
Pancreas is the least common site to be involved by tuberculosis infection. Tubercular pancreatic involvement occurs either through hematogenous, lymphatic, or direct spread from the adjacent organs. However, diagnosis of this rare entity is always challenging. Clinical, laboratory, and imaging features are often nonspecific and tissue analysis is the only way to confirm the diagnosis and avoid unnecessary surgery. Recently, endoscopic ultrasonography-guided fine needle aspiration cytology has emerged as the main modality to make a diagnosis with tissue analysis showing granulomas as the most common findings. Treatment is a standard weight-based antitubercular therapy (ATT) for a duration of 6 months. Occasionally, patients with obstructive jaundice require endoscopic retrograde cholangiogram-guided biliary drainage along with ATT.
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