Abstract
Pancreatic neoplasms in children are rare, representing less than 1% of all solid pediatric tumors. The overall prognosis is generally better than in adults, but some pancreatic neoplasms can be invasive and resistant to adjuvant therapies. Children with pancreatic neoplasms greatly benefit from being managed by pediatric surgeons experienced in pancreatic surgery at high-volume referral centers, since complete surgical resection is a key component of the treatment. The etiology and natural history of pancreatic neoplasms are poorly understood, and although any neoplasms commonly observed in adults can occur in children, the most commonly seen ones hardly ever occur in adults. Pancreatoblastoma (PBT) is the most common pancreatic neoplasm during the first decade of life, and solid-pseudopapillary neoplasm (SPPN) is the most common one during the second decade of life.
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