Abstract

Pancreatic necrosis is a complex and challenging complication of severe acute pancreatitis and it occurs in to of patients with acute pancreatitis It represents one of the most serious complications of severe acute pancreatitis with a mortality rate of to Majority of necrosis are sterile and can be managed conservatively However approximately of pancreatic necrosis develop infection and need an invasive intervention due to aggressive course A minimal invasive step up approach using percutaneous catheter drainage or endoscopic transluminal drainage is currently replacing more invasive open necrosectomy This review provides an overview of patho physiology clinical feature and management of pancreatic necrosis

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