Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach: a case report and review of the literature

Dimitrios Tsapralis,Anastasios Macheras,Dimitrios Schizas,Eva Karamitopoulou,Theodoros Liakakos,Konstantinos Charalabopoulos,Alexandros Charalabopoulos

doi:10.1186/1746-1596-5-4

Abstract

A 60-year-old Caucasian male underwent a total pancreatectomy for a mixed type pancreatic intraductal papillary mucinous neoplasm (IPMN) arising in the main and secondary pancreatic ducts. During surgery, a subserosal polypoid mass was noted at the greater curvature of the gastric antrum and was enucleated. This mass was proven to be heterotopic pancreatic tissue with cystic neoplasia of the IPMN histologic subtype. Through an extensive search of the literature, we found that this is the first case ever reported with simultaneous existence of IPMN changes, in the main and secondary ducts of the orthotopic pancreas and in the heterotopic pancreatic tissue of the gastric wall.

Highlights

Recent literature suggests either an increasing incidence of cystic neoplasms of the pancreas, or improved detection and recognition of these lesions
The most significant recent change in the diagnosis and treatment of pancreatic cystic neoplasms is the recognition of intraductal papillary mucinous neoplasm (IPMN) as a distinct pathologic entity [2,3,4,5,6]
First reported in the literature by Ohashi et al [7], it was classified as a distinct entity from other mucin-producing cystic neoplasms of the pancreas by the World Health Organization (WHO) in 1996 [8]

Summary

Open Access

Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach: a case report and review of the literature.

Introduction

Findings

Discussion