Abstract
Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms that can develop in the entire length of the gastrointestinal tract or sometimes from the omentum and mesentery. In most cases, they arise from the stomach, less often the jejunum or ileum. We report the case of a 53-year-old-female patient, without significant medical history, consulting for chronic epigastric pain, with no other associated signs. She had underwent an abdominal ultrasound completed with a Contrast-enhanced computed tomography (CT) of the abdomen showing a large tissular mass developed at the expense of the cephalic portion of the pancreas, with central calcifications and heterogeneous enhancement after contrast injection. Pancreaticoduodenectomy, partial colectomy and antrectomy has been performed and histological examination with immunohistochemical study had concluded the diagnosis of pancreatic primary GIST.
Highlights
Rare (1% of the digestive tract malignant tumors), gastrointestinal stromal tumors are the most common mesenchymal neoplasms of the gastro intestinal tract
Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms that can develop in the entire length of the gastrointestinal tract or sometimes from the omentum and mesentery
We report the case of a 53-year-old-female patient, without significant medical history, consulting for chronic epigastric pain, with no other associated signs. She had underwent an abdominal ultrasound completed with a Contrast-enhanced computed tomography (CT) of the abdomen showing a large tissular mass developed at the expense of the cephalic portion of the pancreas, with central calcifications and heterogeneous enhancement after contrast injection
Summary
Rare (1% of the digestive tract malignant tumors), gastrointestinal stromal tumors are the most common mesenchymal neoplasms of the gastro intestinal tract They represent a particular pathological entity [1] [2]. GIST are believed to be arisen from, or differentiating along, the interstitial cells of Cajal (ICCs) called “interstitial neural cells” or “intestinal pacemaker cells” and recent studies postulate that GIST arise from multipotential mesenchymal stem cells. Their malignant potential is variable depending on the tumor size and number of mitosis [9] [10]
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