Abstract

The value of the quantitative estimation of pancreatic function is apparent. Interest in pancreatic function really goes back to the time when Einhorn introduced the duodenal tube.<sup>1</sup>Previous to that time, pancreatic functional tests depended on examinations of the feces, which were inaccurate. In these examinations, when many striated muscle fibers, steatorrhea and fatty acid crystals are found, there is generally pronounced dysfunction of the pancreas. Other conditions than pancreatic disease may give positive observations, and often, in distinct pancreatic involvement, the feces tests yield normal reactions, owing to the fact that the enzyme activity of intestinal bacteria has supplanted deficient pancreatic secretion. The Schmidt test,<sup>2</sup>Kashiwado's modification<sup>3</sup>and Einhorn's bead test<sup>4</sup>show also only extreme dysfunction of the pancreas in cases in which the observations are positive. The tests of enzymatic activity in feces as suggested by Gross<sup>5</sup>are also more or less inaccurate, probably more often inaccurate than

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