Abstract
Chronic recurrent multifocal osteomyelitis (CRMO) is the most common autoinflammatory osteopathy. CRMO is characterized by non-bacterial osteomyelitis and primarily affects children and adolescents. The disorder has a relapsing and remitting course. While non-steroidal anti-inflammatory drugs (NSAIDs) are used as first-line treatment, glucocorticoids and disease-modifying antirheumatic drugs have been reported to be effective in some cases. In resistant cases, the effects of TNF-α inhibitors or bisphosphonates were observed.
Highlights
Chronic recurrent multifocal osteomyelitis (CRMO) is the most common autoinflammatory osteopathy
CRMO is characterized by non-bacterial osteomyelitis and primarily affects children and adolescents
While non-steroidal anti-inflammatory drugs (NSAIDs) are used as first-line treatment, glucocorticoids and disease-modifying antirheumatic drugs have been reported to be effective in some cases
Summary
Chronic recurrent multifocal osteomyelitis (CRMO) is the most common autoinflammatory osteopathy. CRMO is characterized by non-bacterial osteomyelitis and primarily affects children and adolescents. The disorder has a relapsing and remitting course. While non-steroidal anti-inflammatory drugs (NSAIDs) are used as first-line treatment, glucocorticoids and disease-modifying antirheumatic drugs have been reported to be effective in some cases. The effects of TNF-a inhibitors or bisphosphonates were observed
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