Abstract
In this small study, pallidal-stimulating electrodes were deliberately placed anteriorly and medially in the globus pallidus interna (GPi) in 6 patients with the prominent motor fluctuations and levodopa-induced dyskinesias characteristic of late-stage Parkinson's disease (PD). In the early postoperative period, the best clinical outcome (a balance between an antidyskinetic effect and improvement in off-related bradykinesia and rigidity) was obtained by activating the most distal electrode contact …
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